Primary carboxamides as btk inhibitors

The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

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Bibliographic Details
Main Authors Osuma, Augustine, Wang, Zhi, Bonafoux, Dominique, Herold, J, Huntley, Raymond, Sheppard, George, Van Camp, Jennifer, Wallace, Grier, Davis, Heather, Somal, Gagandeep, Xu, Xiangdong, Friedman, Michael M, Vasudevan, Anil, Wilson, Noel, Van Epps, Stacy, Frank, Kristine, Wang, Lu, Hoemann, Michael
Format Patent
LanguageEnglish
Published 25.06.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
Bibliography:Application Number: NZ20140754039