Tlr7 agonist crystalline form a, preparation method and use thereof

The present invention relates to crystalline form A of a TLR7 agonist 2-butoxy-7-(4-(pyrrolidin-1-ylmethyl)-benzyl)-5H-pyrrolo[3,2-d]pyrimidin-4-amine (formula I), a method for preparing the crystalline form A, and the use thereof for treating diseases associated with Toll-like receptor 7, such as v...

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Bibliographic Details
Main Authors Zhao, Rui, Ding, Zhaozhong, Wang, Zheng, Yang, Ling, Hu, Yinghu, Zhou, Yilong, Sun, Fei
Format Patent
LanguageEnglish
Published 30.09.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to crystalline form A of a TLR7 agonist 2-butoxy-7-(4-(pyrrolidin-1-ylmethyl)-benzyl)-5H-pyrrolo[3,2-d]pyrimidin-4-amine (formula I), a method for preparing the crystalline form A, and the use thereof for treating diseases associated with Toll-like receptor 7, such as viral infections.
Bibliography:Application Number: NZ20170744884