Α4β7 integrin thioether peptide antagonists

The invention relates to thioether monomer and dimer peptide molecules which inhibit binding of α4β7 to the mucosal addressing cell adhesion molecule (MAdCAM) in vivo.

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Bibliographic Details
Main Authors Zemede, Genet, Frederick, Brian Troy, Bhandari, Ashok, Mattheakis, Larry C, Patel, Dinesh V
Format Patent
LanguageEnglish
Published 27.10.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to thioether monomer and dimer peptide molecules which inhibit binding of α4β7 to the mucosal addressing cell adhesion molecule (MAdCAM) in vivo.
Bibliography:Application Number: NZ20150726337