Production method for 2-fluoro-4-borono-l-phenylalanine, and precursor of 2-fluoro-4-borono-l-phenylalanine
The present invention involves preparing phenylalanine derivatives, wherein the -para position of the phenylalanine side chain is substituted with a chloro, bromo, or iodo group, and the -ortho position is substituted with an excellent leaving group or a direct synthetic intermediate. These phenylal...
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Main Authors | , , , , , , , , |
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Format | Patent |
Language | English |
Published |
26.11.2021
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention involves preparing phenylalanine derivatives, wherein the -para position of the phenylalanine side chain is substituted with a chloro, bromo, or iodo group, and the -ortho position is substituted with an excellent leaving group or a direct synthetic intermediate. These phenylalanine derivatives can be used in a method to efficiently introduce 18F- into the molecule during the later steps in a synthetic scheme. |
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Bibliography: | Application Number: NZ20140720609 |