Smooth muscle cell constructs

Described is an implantable cell-scaffold construct for treating a respiratory disorder in a subject in need comprising: (a) a scaffold comprising a biocompatible matrix having a first surface, wherein the biocompatible matrix is shaped to conform to at least part of a native respiratory organ or ti...

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Bibliographic Details
Main Authors JAIN DEEPAK, RAPOPORT H. SCOTT, SHOKES JACOB E, PAYNE RICHARD, JAYO MANUEL J, RIVERA ELIAS A, LUDLOW JOHN W, BERTRAM LIMOTHY A, SHARP WENDY, JUSTEWICZ DOMINIC M, ILAGAN ROGER M, SANGHA NAMRATA D, HALBERSTADT CRAIG R, QUINLAN SARAH F, BASU JOYDEEP, GENHEIMER CHRISTOPHER W, BOYD SARAH A, KNIGHT OLUWATOYIN A, BURNETTE TERESA B, GUTHRIE KELLY I
Format Patent
LanguageEnglish
Published 29.04.2016
Subjects
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
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Summary:Described is an implantable cell-scaffold construct for treating a respiratory disorder in a subject in need comprising: (a) a scaffold comprising a biocompatible matrix having a first surface, wherein the biocompatible matrix is shaped to conform to at least part of a native respiratory organ or tissue structure in the subject; (b) a smooth muscle cell (SMC) population that is not derived from respiratory tissue deposited on or in the first surface, said biocompatible matrix and said first cell population forming an implantable construct.
Bibliography:Application Number: NZ20110630187