Chaperonin 10 variants

Disclosed is an isolated chaperonin 10 (Cpn10) variant polypeptide sharing at least 90% sequence identity with a wild-type Cpn10 polypeptide comprising a sequence as defined herein wherein said polypeptide has increased binding affinitiy for a pathogen-associatred molecular pattern (PAMP) or has inc...

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Bibliographic Details
Main Authors HOWARD CHRISTOPHER BRUCE, WARD LINDA ALLISON, NAYLOR DEAN JASON, BROWN RICHARD JAMES, VAN HEUMEN WALTER RENE ANTONIUS, STOK JEANETTE ELIZABETH, LAMBERT DANIEL SCOTT, DE BAKKER CHRISTOPHER JOHN, RALSTON KYLIE JANE, JAMES ANDREW LEIGH
Format Patent
LanguageEnglish
Published 28.11.2014
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:Disclosed is an isolated chaperonin 10 (Cpn10) variant polypeptide sharing at least 90% sequence identity with a wild-type Cpn10 polypeptide comprising a sequence as defined herein wherein said polypeptide has increased binding affinitiy for a pathogen-associatred molecular pattern (PAMP) or has increased immunomodulatory function.
Bibliography:Application Number: NZ20100599666