Modifying glycoprotein production in plants
598417 Modifying glycoprotein production in plants Provided is a method for synthesizing a protein of interest with reduced fucosylation and xylosylation comprising, introducing within a plant, a portion of a plant, or a plant cell, a nucleotide sequence encoding a first nucleotide sequence encoding...
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Main Authors | , , , , , , , , , , , |
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Format | Patent |
Language | English |
Published |
28.06.2013
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Subjects | |
Online Access | Get full text |
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Summary: | 598417 Modifying glycoprotein production in plants Provided is a method for synthesizing a protein of interest with reduced fucosylation and xylosylation comprising, introducing within a plant, a portion of a plant, or a plant cell, a nucleotide sequence encoding a first nucleotide sequence encoding beta-1,4-galactosyltransferase (GalT), the first nucleotide sequence operatively linked with a first regulatory region that is active in the plant, and a second nucleotide sequence for encoding the protein of interest, the second nucleotide sequence operatively linked with a second regulatory region that is active in the plant, and transiently co-expressing the first and second nucleotide sequences to synthesize the protein of interest comprising reduced fucosylation and xylosylation. |
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Bibliography: | Application Number: NZ20080598417 |