Stable crystal modifications of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)

Disclosed are crystalline (R,S)-, (R)- or (S)- forms of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) having 2 theta values of 3.6, 5.3, 18.3, 19.3 and 21.7. Further disclosed is a process for the preparation of crystal modifications of the specified crystalline form of DOPC, the use of the crysta...

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Bibliographic Details
Main Authors PLATSCHER, MICHAEL, HEDINGER, ALFRED
Format Patent
LanguageEnglish
Published 27.07.2012
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUSPOLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE
APPARATUS THEREFOR
CHEMISTRY
CRYSTAL GROWTH
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITHDEFINED STRUCTURE
REFINING BY ZONE-MELTING OF MATERIAL
SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITHDEFINED STRUCTURE
SINGLE-CRYSTAL-GROWTH
UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL ORUNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL
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Summary:Disclosed are crystalline (R,S)-, (R)- or (S)- forms of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) having 2 theta values of 3.6, 5.3, 18.3, 19.3 and 21.7. Further disclosed is a process for the preparation of crystal modifications of the specified crystalline form of DOPC, the use of the crystalline DOPC as a constituent for the preparation of a medicament, and a pharmaceutical composition comprising crystal modifications of DOPC.
Bibliography:Application Number: NZ20090590274