GENETIC MARKERS FOR WEIGHT MANAGEMENT AND METHODS OF USE THEREOF

• Main Authors: WILKINS, LEON, RAMAKRISHNAN, SHYAM, KREMPIN, DAVID, PERUSSE, LOUIS, DEBUSK, RUTH, DRAPER, COLLEEN, BRETON, GARY
• Format: Patent
• Language: English
• Published: 30.11.2012
• Subjects: BEER; BIOCHEMISTRY; CALCULATING; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPUTING; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; COUNTING; ELECTRIC DIGITAL DATA PROCESSING; ENZYMOLOGY; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

Provided is a method for selecting a therapeutic/dietary regimen or lifestyle recommendation for a subject comprising: a) assaying a nucleic acid sample obtained from the subject and determining the subject's genotype with respect to the polymorphic loci comprising: FABP2 (rsI799883; G/A) locus; PPARG (rsI801282; C/G) locus; and ADRB2 (rs1042714; C/G) locus; and b) classifying the subject based on said subject's genotype with respect to the polymorphic loci, wherein when the subject's genotype is FABP2 (rs1799883) G/G; PPARG (rs1801282) C/C; and ADRB2 (rs1042714) C/C, then selecting a dietary regimen for the subject, that is a balanced diet.