4(-3-(-2-(PHENYL)MORPHOLINO)-2-OXOPYRROLIDIN-1-YL)-N-(THIAZOL-2-YL)BENZENESULFONAMIDE DERIVATI VES AND RELATED COMPOUNDS AS MODULATORS OF ION CHANNELS FOR THE TREATMENT OF PAIN

• Main Authors: WHITNEY, TARA, MARTINBOROUGH, ESTHER, NEUBERT, TIMOTHY, ZIMMERMANN, NICOLE, STAMOS, DEAN, KAWATKAR, AARTI, SAMEER, NUMA, MEHDI, MICHEL DJAMEL
• Format: Patent
• Language: English
• Published: 25.05.2012
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The disclosure relates to heterocyclic derivatives of formula (I) and pharmaceutically acceptable salts thereof that are useful as inhibitors of ion channels, which makes them suitable for the treatment of various type of pain., (I) or a pharmaceutically acceptable salt thereof, wherein, independent...