PHENYLEPHRINE PHARMACEUTICAL FORMULATION AND COMPOSITIONS FOR COLONIC ABSORPTION

Disclosed is a pharmaceutical composition suitable for oral administration, wherein the composition comprises: a) a core comprising a polymer matrix comprising hydroxypropylcellulose and carboxymethylcellulose sodium salt, and phenylephrine or a pharmaceutically acceptable salt thereof; and b) an er...

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Main Authors ABUTARIF, MALAZ, A, O'MULLANE, JOHN, REO, JOSEPH, P, WAN, JIANSHENG, KABIR, MOHAMMED, A, MONTEITH, DAVID, NOWAK, ROBERT, T, FRITZ, GLENN, E
Format Patent
LanguageEnglish
Published 30.03.2012
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Disclosed is a pharmaceutical composition suitable for oral administration, wherein the composition comprises: a) a core comprising a polymer matrix comprising hydroxypropylcellulose and carboxymethylcellulose sodium salt, and phenylephrine or a pharmaceutically acceptable salt thereof; and b) an erodible layer. The composition is formulated to allow phenylephrine to be absorbed in the colon of a subject.
Bibliography:Application Number: NZ20070573173