Pyrimidine amide compounds as PGDS inhibitors

Disclosed are pyrimidine amide compounds of formula (I) or hydrates, solvates, N-oxides or pharmaceutically salts thereof, wherein R1 is an aryl, heteroaryl or (C5-C6)-cycloalkyl and the rest of the substituents are disclosed within the specification. Also disclosed is the use of the said compound o...

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Main Authors MU, LAN, THURAIRATNAM, SUKANTHINI, MA, LIANG, MUNSON, HARRY RANDALL, ALDOUS, SUZANNE C, JIANG, JOHN ZIQI, SABOL, JEFFREY STEPHEN, LU, JINQI, VANDEUSEN, CHRISTOPHER LOREN
Format Patent
LanguageEnglish
Published 31.03.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed are pyrimidine amide compounds of formula (I) or hydrates, solvates, N-oxides or pharmaceutically salts thereof, wherein R1 is an aryl, heteroaryl or (C5-C6)-cycloalkyl and the rest of the substituents are disclosed within the specification. Also disclosed is the use of the said compound of formula (I) for the preparation of a medicament for the treatment of an allergic or inflammatory disorder.
Bibliography:Application Number: NZ20060567208