Substituted aminoalkyl- and amidoalkyl-benzopyran derivatives

• Main Authors: THALER, FLORIAN, CAROTTI, ANGELO, CACCIA, CARLA, SALVATI, PATRICIA, MELLONI, PIERO, MAESTRONI, SARA
• Format: Patent
• Language: English
• Published: 29.01.2010
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Disclosed are aminoalkyl- and amidoalkyl-benzopyran derivatives of formula (I) and the pharmaceutically acceptable salts thereof, wherein the variables are as defined in the specification. These compounds are active as selective and reversible monoamine oxidase type B (MAO-B) inhibitors in vitro and...