Imidazo[4,5-B]pyridin-2-one and oxazolo[4,5-B]pyridin-2-one compounds and analogs thereof as therapeutic compounds

Disclosed are imidazo[4,5-B]pyridine-2-one and oxazolo[4,5-B]pyridine-2-one compounds of the formula as depicted, pharmaceutically acceptable salts and solvates thereof, pharmaceutical compositions thereof and their use in treating cell proliferation, cancer and disease of conditions that are amelio...

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Main Authors SPRINGER, CAROLINE JOY, GILL, ADRIAN LIAM, ROMAN VELA, ESTEBAN, GAULON, CATHERINE, TAYLOR, RICHARD DAVID, MARAIS, RICHARD MALCOLM, MENARD, DELPHINE, DIJKSTRA, HARMEN, NICULESCU-DUVAZ, DAN
Format Patent
LanguageEnglish
Published 29.10.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed are imidazo[4,5-B]pyridine-2-one and oxazolo[4,5-B]pyridine-2-one compounds of the formula as depicted, pharmaceutically acceptable salts and solvates thereof, pharmaceutical compositions thereof and their use in treating cell proliferation, cancer and disease of conditions that are ameliorated by the inhibition of RAF.
Bibliography:Application Number: NZ20050555005