2-propynyl adenosine analogs with modified 5'-ribose groups having A2A agonist activity

Disclosed is a compound having formula (I) wherein the substituents are disclosed within the specification; or a pharmaceutically acceptable salt thereof. Also disclosed is the use of a compound of formula (I) for the preparation of a medicament fore preventing or treating a pathological condition o...

Full description

Saved in:
Bibliographic Details
Main Authors LINDEN, JOEL M, FIGLER, ROBERT ALAN, MURPHREE, LAUREN J, MACDONALD, TIMOTHY L, RIEGER, JAYSON M, SULLIVAN, GAIL W
Format Patent
LanguageEnglish
Published 24.12.2010
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
Online AccessGet full text

Cover

More Information
Summary:Disclosed is a compound having formula (I) wherein the substituents are disclosed within the specification; or a pharmaceutically acceptable salt thereof. Also disclosed is the use of a compound of formula (I) for the preparation of a medicament fore preventing or treating a pathological condition or symptom in a mammal wherein the activity of A3 adenosine receptors is implicated and agonism of such activity is desired such as an inflammatory response.
Bibliography:Application Number: NZ20050553288