Use of apoptosis-specific EIF-5A sirnas for the manufacture of a medicament for use in the treatment of a disease treatable by suppression of the JAK/STAT pathway

Disclosed is the use of an siRNA of an apoptosis specific eIF-5A in the manufacture of a medicament for use in the treatment of a condition treatable by suppression of the activation of the JAAK/STAT pathway, wherein said siRNA suppresses activation of the JAK/STAT pathway in a cell.

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Bibliographic Details
Main Authors REZNIKOV, LEONID, THOMPSON, JOHN E, TAYLOR, CATHERINE, GALTON, BRUCE C, DINARELLO, CHARLES, HOPKINS, MARIANNE, BOONE, ADRIENNE
Format Patent
LanguageEnglish
Published 27.08.2010
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:Disclosed is the use of an siRNA of an apoptosis specific eIF-5A in the manufacture of a medicament for use in the treatment of a condition treatable by suppression of the activation of the JAAK/STAT pathway, wherein said siRNA suppresses activation of the JAK/STAT pathway in a cell.
Bibliography:Application Number: NZ20050552692