Method of identifying individuals at risk of thiopurine drug resistance and intolerance - GMPS

Disclosed is a method of screening individuals to determine if the individual is at risk of thiopurine resistance or intolerance. The method comprises determining the genotypic state of an individual with respect to the GMPS gene and screening the individual for the presence or absence of one or mor...

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Bibliographic Details
Main Authors BARCLAY, MURRAY LINDSAY, KENNEDY, MARTIN ALEXANDER, ROBERTS, REBECCA LEE, GEARRY, RICHARD BLAIR
Format Patent
LanguageEnglish
Published 30.06.2008
Edition7
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Summary:Disclosed is a method of screening individuals to determine if the individual is at risk of thiopurine resistance or intolerance. The method comprises determining the genotypic state of an individual with respect to the GMPS gene and screening the individual for the presence or absence of one or more polymorphisms selected from SEQ ID NO:2 to SEQ ID NO:5.
Bibliography:Application Number: NZ20060551157