Inhibition of apoptosis-specific eIF-5A ("eIF-5A1") with antisense oligonucleotides and siRNAs as anti-inflammatory therapeutics
Disclosed is an siRNA of apoptosis specific eukaryotic initiation factor 5A (eIF-5A) wherein said siRNA suppresses endogenous expression of apoptosis-specific eIF-5A in a cell and wherein the apoptosis specific eIF-5A is encoded by the nucleotide sequence of SEQ ID NO:30, SEQ ID NO:31, SEQ ID NO:32...
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Main Authors | , , , , , , , , |
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Format | Patent |
Language | English |
Published |
30.04.2009
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Summary: | Disclosed is an siRNA of apoptosis specific eukaryotic initiation factor 5A (eIF-5A) wherein said siRNA suppresses endogenous expression of apoptosis-specific eIF-5A in a cell and wherein the apoptosis specific eIF-5A is encoded by the nucleotide sequence of SEQ ID NO:30, SEQ ID NO:31, SEQ ID NO:32 or SEQ ID NO:33. The disclosed siRNA can be mixed with water and administered intranasally as a medicament. |
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Bibliography: | Application Number: NZ20040544159 |