Methods and compositions for the enzymatic synthesis of gangliosides

Disclosed is a compound having formula (I) wherein: Z is a member selected from O, S, C(R2)2 and NR2; X is a member selected from H, -OR3, -NR3R4, -SR3 and -CHR3R4; Y is a member selected from H, -OR7, -SR7, -NR7R8, substituted or unsubstituted alkyl, alkenyl, alkynyl, heteroalkyl, aryl, heteroaryl,...

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Bibliographic Details
Main Authors WANG, ZHI-GUANG, DEFREES, SHAWN, JOHNSON, KARL FRANK
Format Patent
LanguageEnglish
Published 30.05.2008
Edition7
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HETEROCYCLIC COMPOUNDS
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Summary:Disclosed is a compound having formula (I) wherein: Z is a member selected from O, S, C(R2)2 and NR2; X is a member selected from H, -OR3, -NR3R4, -SR3 and -CHR3R4; Y is a member selected from H, -OR7, -SR7, -NR7R8, substituted or unsubstituted alkyl, alkenyl, alkynyl, heteroalkyl, aryl, heteroaryl, or heterocycloalkyl; R1 is of the formula -C(R11)=CR12R13; and the remaining substituents are as disclosed in the specification. Compounds of the formula disclosed are useful in the prevention or treatment of disorders of the nervous system.
Bibliography:Application Number: NZ20040542148