Sulfonylamino-derivatives as novel inhibitors of histone deacetylase

Disclosed are compounds of formula (I), wherein: Each of Q, X. Y and Z is nitrogen or C, ring A is a optionally substituted carbocyclic or heterocyclic ring, and the remaining substituents are defined herein. The compounds are used for the manufacture of medicaments for treating proliferative diseas...

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Main Authors BACKX, LEO JACOBUS JOZEF, PILATTE, ISABELLE NOELLE CONSTANCE, DE WINTER, HANS LOUIS JOS, VAN BRANDT, SVEN FRANCISCUS ANNA, VAN HEUSDEN, JIMMY ARNOLD VIVIANE, ANGIBAUD, PATRICK RENE, VERDONCK, MARC GUSTAAF CELINE, VAN EMELEN, KRISTOF
Format Patent
LanguageEnglish
Published 28.04.2006
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:Disclosed are compounds of formula (I), wherein: Each of Q, X. Y and Z is nitrogen or C, ring A is a optionally substituted carbocyclic or heterocyclic ring, and the remaining substituents are defined herein. The compounds are used for the manufacture of medicaments for treating proliferative diseases.
Bibliography:Application Number: NZ20030534771