Process for the production of 16,17-[(cyclohexylmethylene) bis(oxy)]-11,21-dihydroxy-pregna-1,4-diene-3,20-dione or its 21-isobutyrate by transketalisation

Disclosed is a process for the preparation of a compound of formula 1, in which R is hydrogen or isobutyryl, the process comprising: reacting a compound of formula 2, in which R is hydrogen or isobutyryl, R1 is alkyl, and R2 is alkyl, with cyclohexanealdehyde.

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Bibliographic Details
Main Author SCHMIDT, BEATE
Format Patent
LanguageEnglish
Published 26.11.2004
Edition7
Subjects
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Summary:Disclosed is a process for the preparation of a compound of formula 1, in which R is hydrogen or isobutyryl, the process comprising: reacting a compound of formula 2, in which R is hydrogen or isobutyryl, R1 is alkyl, and R2 is alkyl, with cyclohexanealdehyde.
Bibliography:Application Number: NZ20010525707