Treatment of emesis using tetrahydrobenz[cd]indole-6-carboxamides

The specification describes the use of known tetrahydrobenz[cd] indoles of the above general formula to treat emesis. Variables R1-R4 are as follows: R1 is H, C2-C4 alkyl or allyl, R2 is H, C2-C4 alkyl or allyl, R3 and R4 are each H, C1-C4 alkyl substituted with a phenyl group or; Together they may...

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Bibliographic Details
Main Authors FOREMAN, MARK MORTENSEN, LEANDER, J DAVID
Format Patent
LanguageEnglish
Published 24.11.2000
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The specification describes the use of known tetrahydrobenz[cd] indoles of the above general formula to treat emesis. Variables R1-R4 are as follows: R1 is H, C2-C4 alkyl or allyl, R2 is H, C2-C4 alkyl or allyl, R3 and R4 are each H, C1-C4 alkyl substituted with a phenyl group or; Together they may form a C3-C5 heterocyclic ring, With the proviso that only one of R3 and R4 can be hydrogen.
Bibliography:Application Number: NZ19940314570