METHODS OF HYDROLYSIS (OPTIONALLY STEREOSELECTIVELY) OF ESTERS AND (TRANS)ESTERIFICATION (OPTIONALLY STEREOSELECTIVELY) USING ENZYMES, ESPECIALLY FROM CANDIDA RUGOSA; AND CANDIDA RUGOSA ENZYMES

Process for stereoselectively hydrolyzing esters or esterifying acids with lipase preparations of Candida rugosa in aqueous/organic systems, where the acid is not substituted at the 2-position with a halogen, e.g. process for the production of R-2-(4-hydroxyphenoxy)propionic acid at high en tiomeric...

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Bibliographic Details
Main Authors MALICK, ADRIEN P, CALTON, GARY J, LIN, PENG, HAMMAN, JOHN P, ANIMESH GOSWAMI, COBBS, CARRINGTON S, BARTON, MICHAEL J
Format Patent
LanguageEnglish
Published 25.06.1992
Edition5
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Process for stereoselectively hydrolyzing esters or esterifying acids with lipase preparations of Candida rugosa in aqueous/organic systems, where the acid is not substituted at the 2-position with a halogen, e.g. process for the production of R-2-(4-hydroxyphenoxy)propionic acid at high en tiomeric excess. Additionally disclosed is a process for separating and purifying the isozymes from the lipase of Candida rugosa and their use for the stereoselective hydrolysis of esters, transesterification of esters and esterification of acids.
Bibliography:Application Number: NZ19900233849