PREPARATION OF 2,3,4,5-TETRAFLUOROBENZOYL ACETATES

An improved process for the preparation of methyl 2,3,4,5-tetrafluorobenzoylacetate is described. The process is for intermediates that lead to trifluoroquinolinic acids which in turn are used to produce antibacterial agents of the difluoro quinolinecarboxylic acid type. The process runs at room tem...

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Bibliographic Details
Main Authors BEYLIN, V G, GOEL, O P
Format Patent
LanguageEnglish
Published 27.09.1989
Edition4
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:An improved process for the preparation of methyl 2,3,4,5-tetrafluorobenzoylacetate is described. The process is for intermediates that lead to trifluoroquinolinic acids which in turn are used to produce antibacterial agents of the difluoro quinolinecarboxylic acid type. The process runs at room temperature, uses a safe inexpensive base, and can be conveniently scaled up for manufacturing purposes.
Bibliography:Application Number: NZ19870219819