Et nytt purinderivat

• Main Authors: HIROTA, KOHSAKU, SATOH, HARUMI, TAKAKU, HARUO, OGITA, HARUHISA, CHIBA, NOBUYOSHI, ISOBE, YOSHIAKI, MATSUI, HIROYUKI
• Format: Patent
• Language: Norwegian
• Published: 30.04.1998
• Edition: 6
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

A purine derivative represented by the following general formula (I): wherein R is a hydrogen atom or a hydrocarbon group containing at most 14 carbon atoms; any -CH2- group in said hydrocarbon group may be replaced with a carbonyl group, a sulfonyl group, -O- or -S- when said -CH2- group is not directly attached to the purine ring or is in -CH3 group not directly attached to the purine ring; any =CH2 group may be replaced with =O or =S; C-H group in said hydrocarbon group may be replaced with N, a C-halogen group or a C-CN group when said C-H group is in -CH2-group not directly attached to the purine ring, in -CH3 group not directly attached to the purine ring, in >CH-group not directly attached to the purine ring, in =CH-group not directly attached to the purine ring or in =CH2 group; R is a hydroxyl group, an amino group or an amino group mono- or di-substituted with a hydrocarbon group containing at most 10 carbon atoms; R is a hydroxyl group, a mercapto group, an acyloxy group containing at most 18 carbon atoms or an oxycarbonyloxy group substituted with a hydrocarbon group containing at most 19 carbon atoms; R is a hydrocarbon group containing at most 14 carbon atoms; any -CH2- group in said R may be replaced with a carbonyl group, a sulfonyl group, -O- or -S- when said -CH2- group is not directly attached to the purine ring or is in -CH3 group not directly attached to the purine ring; any =CH2 group may be replaced with =O or =S; C-H group in said R may be replaced with N, a C-halogen group or a C-CN group when said C-H group is in -CH2-group not directly attached to the purine ring, in -CH3 group not directly attached to the purine ring, in >CH-group not directly attached to the purine ring, in =CH-group not directly attached to the purine ring, in =CH2 group or in IDENTICAL CH group; or its tautomer or pharmaceutically acceptable salts thereof, and an interferon inducer, an anti-virus agent or an anti-cancer agent which comprises said purine derivative or pharmaceutically acceptable salts thereof as an active ingredient.