NO753291L

• Main Authors: KELLER-JUSLEN C, PACHE W, KUHN M
• Format: Patent
• Language: English
• Published: 08.04.1976
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOUNDS OF UNKNOWN CONSTITUTION; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPIRITS; VINEGAR; WINE

Fremgangsmåte for fremstilling av nye_antibiotika. 1527494 Antibiotic SANDOZ Ltd 2 Oct 1975 [7 Oct 1974 12 Dec 1974 12 Feb 1975 7 April 1975 24 July 1975] 40301/75 Heading C2C A process for producing a compound selected from antibiotics SL 7810/F, SL 7810/F-II and SL 7810/F-III and their tetrahydro derivatives comprises (a) cultivating a SL 7810/F and/or SL 7810/F-II and/or SL 7810/F-III producing strain of Aspergillus rugulosus Thorn and Raper in the presence of a nutrient medium to produce one or more of the above antibodies or (b) hydrogenating an antibiotic chosen from SL 7810/F, SL 7810/F-II and SL 7810/F-III to produce the corresponding tetrahydro derivative. The strain used is suitably NRRL 8039. The compound may be mixed with a suitable diluent or carrier to form a pharmaceutical composition. Antibiotic SL 7810/F has the formula wherein R is Antibiotic SL 7810/FII has the formula wherein R is as above. Antibiotic SL 7810/F-III has the formula wherein R is as above.