Sammensetninger og fremgangsmåter for fremstilling av lite vannoppløselige medikamenter med økt stabilitet

The present invention provides stable pharmaceutical compositions of poorly water soluble pharmaceutical agents and stabilizing agents which function to increase stability of the compositions. The use of stabilizing agents provide extended stability of nanoparticle suspensions and other formulations...

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Bibliographic Details
Main Authors Desai, Neil P, Yang, Andrew, De, Tapas, Yim, Zachary, Soon-Shiong, Patrick M D
Format Patent
LanguageNorwegian
Published 11.06.2019
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention provides stable pharmaceutical compositions of poorly water soluble pharmaceutical agents and stabilizing agents which function to increase stability of the compositions. The use of stabilizing agents provide extended stability of nanoparticle suspensions and other formulations of poorly water soluble pharmaceutical agents such as docetaxel under certain conditions, for example upon dilution for administration.
Bibliography:Application Number: NO20080001576