(S)-(-)-1-(4-fluorisokinolin-5-yl)-sulfonyl-2-metyl-1,4-homopiperazinhydrokloriddihydrat samt fremgangsmåte for fremstilling av samme

The present invention is directed to (S)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride dihydrate, to a method producing the dihydrate, and to a drug composition containing the dihydrate. The compound of the present invention has less hygroscopicity as compared wi...

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Bibliographic Details
Main Authors Ohshima, Takeshi, Onogi, Kazuhiro, Hidaka, Hiroyoshi, Shiratsuchi, Masami, Oda, Toshiaki
Format Patent
LanguageNorwegian
Published 07.11.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention is directed to (S)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride dihydrate, to a method producing the dihydrate, and to a drug composition containing the dihydrate. The compound of the present invention has less hygroscopicity as compared with (S)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride anhydrous crystals and thus, exhibits excellent chemical stability.
Bibliography:Application Number: NO20070002382