Kjemiske forbindelser, farmasoeytisk preparat med blodplateaggregeringshemmende egenskaper, samt anvendelse av forbindelsene til fremstilling av henholdsvis en blodplateaggregeringsinhibitor og et farmasoeytisk preparat for behandling eller foreby

A compound represented by general formula (I) and having a platelet aggregation inhibitor effect and pharmacologically acceptable salt and solvate thereof, wherein A, B and C represent each CH2 or C=O; X and Y are different from each other and represent CH or N; D represents -(CH2)k- or -(CH2)m-CO-,...

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Main Authors HATSUSHIBA, EMIKO, SHIMIZU, MASARO, OHKURA, NAOTO, ISOMURA, YASUKO, IIDA, HIROYUKI, ASAI, KENJI, OHUCHI, SHOKICHI, MIURA, TOMOAKI, SHITARA, EIKI, KATANO, KIYOAKI, YAEGASHI, KAZUE, ISHIKAWA, MIDORI
Format Patent
LanguageNorwegian
Published 23.08.1999
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A compound represented by general formula (I) and having a platelet aggregation inhibitor effect and pharmacologically acceptable salt and solvate thereof, wherein A, B and C represent each CH2 or C=O; X and Y are different from each other and represent CH or N; D represents -(CH2)k- or -(CH2)m-CO-, wherein k represents an integer of 1 to 4, and m represents an integer of 0 to 3; E represents group (II) or (III), wherein n represents an integer of 1 to 3, Z represents -W-(CH2)p-COOR , W represents -O- or a bond, p represents an integer of 1 to 4, and R represents hydrogen, lower alkyl or an ester residue eliminable under physiological conditions; R represents hydrogen or lower alkyl; and R represents hydrogen or lower alkyl.
Bibliography:Application Number: NO19960000919