Antitumor celleantigen antistoff terapi

• Main Authors: JANTAPOUR MARY J, YU GUOYING K
• Format: Patent
• Language: Norwegian
• Published: 23.12.2008
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

Sammendrag Fremgangsmåter for å diagnostisere, detektere eller behandle cancer hvor canceren uttrykker et tumorcelleantigen som er forhøyet relativt til det normale tilsettende vevet, ved å administrere et antistoff eller antistoffragment som binder til det tumorcelleantigenet. Fremgangsmåtene involverer anvendelsen av antistoffer som binder til tumorcelleantigenene KIAA1815, LOC157378, FU20421, DSCD75, GPRI60, GPCR41 og SLC I A5. Methods of diagnosing, detecting or treating cancer where the cancer expresses a tumor cell antigen that is elevated relative to the normal adjacent tissue, by administering an antibody or antibody fragment which binds to that tumor cell antigen. The methods involve the use of antibodies that bind to the tumor cell antigens KIAA1815, LOC157378, FU20421, DSCD75, GPR160, GPCR41, and SLC1A5.