Nitrogenholdige aromatiske ringforbindelser

• Main Authors: FUNAHASHI, YASUHIRO, FUKUDA, YOSHIO, MATSUSHIMA, TOMOHIRO, MATSUI, KENJI, WATANABE, TATSUO, HANEDA, TORU, YAMAGUCHI, ATSUMI, MIMURA, FUSAYO, TSURUOKA, AKIHIKO, MATSUKURA, MASAYUKI, SUZUKI, SACHI, YOSHIBA, TAKAKO, KAMATA, JUNICHI, NOMOTO, KEN-ICHI, NAKAMURA, KATSUJI, MIYAZAKI, KAZUKI, TAKAHASHI, KEIKO, YAMAMOTO, YUJI, MATSUI, JUNJI, OBAISHI, HIROSHI
• Format: Patent
• Language: Norwegian
• Published: 19.06.2003
• Edition: 7
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Forbindelser representert ved den generelle formel (1) eller salter derav, eller et hydrat av begge: (I) hvor Ag er en eventuelt substituert 5- til 14-leddet heterocyklisk gruppe eller lignende; Xer -O-, -S- eller lignende; Yer eventuelt substituert C6-14 aryl, en 5- til 14-leddet heterocyklisk gruppe eller lignende; og Ter en gruppe med generell formel (II) eller lignende: (II) [hvor Eg er en enkeltbinding, -N(R)- eller lignende; Rog Rer hver uavhengig hydrogen, eventuelt substituert Q.6 alkyl eller lignende; og Zer C-alkyl, C-alicyklisk hydrokarbyl, C6-uaryl eller lignende]. The present invention concerns a process for preparing a compound represented by the following general formula (a- or a pharmacologically acceptable salt or hydrate thereof, which comprises reacting a compound repr with a compound represented by the following general formula (a-4) : wherein the residues R 1 , R 2 , R sa1 - R sa3 , R 300 , R 301 and Z are as defined in the claims.