FREMGANGSMAATE FOR FREMSTILLING AV 2,2`-ANHYDRO-1BETA-D-ARABINFURANOSYL-5-CYTOSIN

2,2'-Anhydro-1 beta -D-arabinofuranosyl-5-fluorocytosine (hereafter AAFC) and its acid addition salts are known compounds. AAFC may now be conveniently prepared in extremely high yield by selective acid catalyzed hydrolysis of the corresponding 3'-O-acyl analogs of AAFC which unexpectedly...

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Bibliographic Details
Main Author HOFFER, MAX
Format Patent
LanguageNorwegian
Published 03.04.1978
Subjects
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Summary:2,2'-Anhydro-1 beta -D-arabinofuranosyl-5-fluorocytosine (hereafter AAFC) and its acid addition salts are known compounds. AAFC may now be conveniently prepared in extremely high yield by selective acid catalyzed hydrolysis of the corresponding 3'-O-acyl analogs of AAFC which unexpectedly hydrolyzes at the acyl group while the 2,2'-anhydro linkage remains intact.
Bibliography:Application Number: NO19730005007