Benzopyranverbindingen voor gebruik bij de behandeling en preventie van ontstekingsgerelateerde aandoeningen

The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R1, R2, R3, and R4 are as described in the...

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Main Authors ANGELA M. DEPROW, DAVID LOUIS BROWN, JAMES RICHARD KIEFER JR, YI YU, SOFYA TSYMBALOV, RENEE M. HUFF, SUBO LIAO, JEFFREY STEVEN CARTER, BRUCE CAMERON HAMPER, JOHN ROBERT SPRINGER, KARL WILLIAM ASTON, E. ANN HALLINAN, LIJUAN JANE WANG, LI XING, DAVID CHRISTOPHER LIMBURG, THERESA R. FLETCHER, STEVEN W. KRAMER, FRANCIS KOSZYK
Format Patent
LanguageDutch
Published 01.03.2005
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R1, R2, R3, and R4 are as described in the specification.
Bibliography:Application Number: NL20041025844