FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME

The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment...

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Main Authors SPINK, BENJAMIN, DING, SHENG, STEMMER, WILLEM, P, JIANG, HAIYAN, PETERS, ROBERT, LIU, TONGYAO, TOBY, GARABET, G, CHANG, PEI-YUN, VARFAJ, FATBARDHA, SCHELLENBERGER, VOLKER, MEI, BAISONG, SILVERMAN, JOSHUA, KULMAN, JOHN, WANG, CHIA-WEI, WANG, DEPING, GEETHING, NATHAN
Format Patent
LanguageEnglish
Published 12.01.2022
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.
Bibliography:Application Number: MY2014PI02385