USE OF TOPICAL COMPOSITION CONTAINING EPIDERMAL GROWTH FACTOR (EGF) FOR DIABETIC FOOT AMPUTATION PREVENTION

The present invention is related to the use of topical formulations that contain epidermal growth factor encapsulated in or associated to deformable or conventional liposomes to be applied on the surface of and around chronic ischemic skin lesions. The formulations of the present invention, in contr...

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Main Authors PAEZ MEIRELES, ROLANDO, PUPO ESCALONA, ELDER, BERLANGA ACOSTA, JORGE AMADOR, BETANCOURT RODRIGUEZ, BLAS YAMIR
Format Patent
LanguageEnglish
Published 19.03.2021
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Summary:The present invention is related to the use of topical formulations that contain epidermal growth factor encapsulated in or associated to deformable or conventional liposomes to be applied on the surface of and around chronic ischemic skin lesions. The formulations of the present invention, in contrast with the previous art, are useful because they provide a high bioavailability of EGF in the tissue deep below the lesions and for preventing diabetic foot amputation. (Figure 1)
Bibliography:Application Number: MY2008PI02429