MICROORGANISM HAVING CARBON DIOXIDE FIXATION CYCLE INTRODUCED THEREINTO

• Main Authors: MADHAVAN, Anjali, MATSUMOTO, Yoshiko, CHONG, SU SUN, HIDESAKI, Tomonori, FUJII, Ryota
• Format: Patent
• Language: English
• Published: 12.11.2019

An acetyl-CoA producing microorganism obtained by imparting at least one enzymatic activity selected from the group consisting of malate thiokinase, malyl- CoA lyase, glyoxylate carboligase, 2-hydroxy-3-oxopropionate reductase, and hydroxypyruvate reductase, to a microorganism that does not have any of the following (a), (b), (c), (d) or (e): (a) a carbon dioxide fixation cycle including an enzymatic reaction from malonyl-CoA to malonate semialdehyde or 3- hydroxypropionate; (b) a carbon dioxide fixation cycle including an enzymatic reaction from acetyl-CoA and CO2 to pyruvate; (c) a carbon dioxide fixation cycle including an enzymatic reaction from crotonyl-CoA and CO2 to ethylmalonyl-CoA or glutaconyl-CoA; (d) a carbon dioxide fixation cycle including an enzymatic reaction from CO2 to formate; or (e) at least one selected from the group consisting of malate thiokinase and malyl-CoA lyase.