NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS

The present invention discloses compounds according to Formula I: Wherein R13, R1\ R2, R4, R5, R63, R6 7 8 W, X, Cy, and the subscript a are as defined herein. The present invention relates to compounds inhibiting autotaxin (NPP2 or ENPP2), methods for their production, pharmaceutical compositions c...

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Main Authors HECKMANN, BERTRAND, BRYS, REGINALD CHRISTOPHE XAVIER, DESROY, NICOLAS, PEIXOTO, CHRISTOPHE, JONCOUR, AGNES, BOCK, XAVIER
Format Patent
LanguageEnglish
Published 13.07.2019
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Summary:The present invention discloses compounds according to Formula I: Wherein R13, R1\ R2, R4, R5, R63, R6 7 8 W, X, Cy, and the subscript a are as defined herein. The present invention relates to compounds inhibiting autotaxin (NPP2 or ENPP2), methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving fibrotic diseases, proliferative diseases, inflammatory diseases, autoimmune diseases, respiratory diseases, cardiovascular diseases, neurodegenerative diseases, dermatological disorders, and/or abnormal angiogenesis associated diseases by administering the compound of the invention.
Bibliography:Application Number: MY2015PI703027