AN ALLERGENIC PROTEIN COMPLEX OF NATURAL RUBBER LATEX

• Main Authors: ELUMALAI SUNDERASAN, SITI ARIJA MAD ARIF, HOONG YEET YEANG
• Format: Patent
• Language: English
• Published: 30.05.2014
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; DERIVATIVES THEREOF; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; SUGARS; TESTING; VINEGAR; WINE

THE INVENTION RELATES TO THE ALLERGENIC LATEX PROTEIN HEV B 4. THE FULL cDNA SEQUENCE OF THE SMALLER PROTEIN COMPONENTS OF HEV B 4 IS DISCLOSED, TOGETHER WITH THE AMINO ACID SEQUENCE OF THOSE COMPONENTS AND THE SYNTHESIS OF A RECOMBINANT PROTEIN USING THE AFORESAID DNA SEQUENCE OR A SYNTHETIC PEPTIDE DERIVED FROM THE AMINO ACID SEQUENCE. THE USE OF THE HEV B 4 PROTEIN COMPLEX AND OF AN ANTIBODY AGAINTS THAT PROTEIN IS DESCRIBED IN IMMUNOASSAYS AND IN IMMUNOTHERAPY FOR THE RELIEF OF ALLERGY OR ALLERGY SYMPTOMS.