( 4-ARYLSULFAMINO )-TETRAHYDROPYRAN-4-CARBOXYLIC ACID HYDROXAMIDES

A COMPOUND OF THE FORMULA WHEREIN Q IS AS DEFINED ABOVE, ARE USEFUL IN THE TREATMENT OF A CONDITION SELECTES FROM THE GROUP CONSISTING OF ARTHRITIS (INCLUDING OSTEARTHRITIS AND RHEUMATOID ARTHRITIS), INFLAMMATORY BOWEL DISEASE, CROHN''S DISEASE, EMPHYSEMA, CHRONIC OBSTRUCTIVE PULMONARY DIS...

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Bibliographic Details
Main Author LAWRENCE ALAN REITER
Format Patent
LanguageEnglish
Published 31.10.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A COMPOUND OF THE FORMULA WHEREIN Q IS AS DEFINED ABOVE, ARE USEFUL IN THE TREATMENT OF A CONDITION SELECTES FROM THE GROUP CONSISTING OF ARTHRITIS (INCLUDING OSTEARTHRITIS AND RHEUMATOID ARTHRITIS), INFLAMMATORY BOWEL DISEASE, CROHN''S DISEASE, EMPHYSEMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ALZHEIMER''S DISEASE, ORGAN TRANSPLANT TOXICITY, CACHEXIA, ALLERGIC REACTIONS, ALLERGIC CONTACT HYPERSENSITIVITY, CANCER, TISSUE ULCERATION, RESTENOSIS, PERIODONTAL DISEASE, EPIDERMOLYSIS BULLOSA, OSTEOPOROSIS, LOOSENING OF ARTIFICIAL JOINT IMPLANTS, , ATHEROSCLEROSIS (INCLUDING ATHEROSCLEROTIC PLAQUE RUPTURE, AORTIC ANEURYSM 9INCLUDING ABDOMINAL AORTIC ANEURYSM AND BRAIN AORTIC ANEURYSM), CONGESTIVE HEART FAILURE, MYOCARDIAL INFARCTION, STROKE, CEREBRAL ISCHEMIA, HEAD TRAUMA, SPINAL CORD INJURY, NEURO-DEGENERATIVE DISORDERS (ACUTE AND CHRONIC), AUTOIMMUNE DISORDERS, HUNTINGTON''S DISEASE, PARKINSON''S DISEASE, MIGRAINE, DEPRESSION, PERIPHERAL NEUROPARHY, PAIN, CEREBRAL AMYLOID ANGIOPATHY, NOOTROPIC OR COGNITION ENHANCEMENT AMYOTROPHIC LATERAL SCLEROSIS, MULTIPLE SCLEROSIS, OCULAR ANGIOGENESIS , CORNEAL INJURY, MACULAR DEGENERATION, ABNORMAL WOUND HEALING, BURNS, DIABETES, TUMOR INVASION, TUMOR GROWTH, TUMOR METASTASIS, COMEAL SCARRING, SCLERITIS, AIDS, SEPSIS AND SEPTIC SCHACK. IN ADDITION, THE COMPOUNDS OF THE PRESENT INVENTION MAY BE USED IN COMBINATION THERAPY WITH STANDARD NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAID''S) AND ANALGESICS, AND IN COMBINATION WITH CYTOTOXICDRUGS SUCH AS ADRIAMYCIN, DAUNOMYCIN, CIS-PLATINUM, ETOPOSIDE, TAXOL, TAXOTERE AND OTHER ALKALOIDS, SUCH AS VINCRISTINE, IN THE TREATMENT OF CANCER.
Bibliography:Application Number: MY1999PI01355