CRYSTALLINE EFAVIRENZ

THE POTENT REVERSE TRANSCRIPTASE INHIBITOR EFAVIRENZ IS PRODUCED IN CRYSTALLINE FORM. CRYSTALLINE EFAVIRENZ EXISTS IN SEVERAL PHYSICAL FORMS WHICH ARE DESIGNATED FORM 1, 2, 3, 4, AND 5 AND ARE CHARACTERIZED BY X-RAY POWDER DIFFERACTION AND DIFFERENTIAL SCANNING CALORIMENTRY. PHARMACEUTICAL COMPOSITI...

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Bibliographic Details
Main Authors MICHAEL B. MAURIN, SHELLEY R. RABEL, JAMES R. MOORE, LILIAN A. RADESCA
Format Patent
LanguageEnglish
Published 31.10.2006
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:THE POTENT REVERSE TRANSCRIPTASE INHIBITOR EFAVIRENZ IS PRODUCED IN CRYSTALLINE FORM. CRYSTALLINE EFAVIRENZ EXISTS IN SEVERAL PHYSICAL FORMS WHICH ARE DESIGNATED FORM 1, 2, 3, 4, AND 5 AND ARE CHARACTERIZED BY X-RAY POWDER DIFFERACTION AND DIFFERENTIAL SCANNING CALORIMENTRY. PHARMACEUTICAL COMPOSITIONS AND METHODS ARE USEFUL FOR THE TREATMENT OF THE HUMAN IMMUNODEFICIENCY VIRUS (HIV).(FIG 2)
Bibliography:Application Number: MY1919PI992384