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The invention concerns a compound of the Formula (I) wherein m is 0-2 and each R1 is a group such as hydroxy, halogeno, trifluoromethyl heterocyclyl and heterocyclyloxy; R2 is halogeno, trifluoromethyl or (1-6C)alkyl; R3 is hydrogen, halogeno or (1-6C)alkyl; and R4 is (3-6C)cycloalkyl;or pharmaceuti...

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Bibliographic Details
Main Author IAN ALUN NASH
Format Patent
LanguageEnglish
Spanish
Published 20.06.2006
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention concerns a compound of the Formula (I) wherein m is 0-2 and each R1 is a group such as hydroxy, halogeno, trifluoromethyl heterocyclyl and heterocyclyloxy; R2 is halogeno, trifluoromethyl or (1-6C)alkyl; R3 is hydrogen, halogeno or (1-6C)alkyl; and R4 is (3-6C)cycloalkyl;or pharmaceutically-acceptable salts thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical condions mediated by cytokines. La invencion concierne a un compuesto de la Formula (I) (ver formula I) en donde m es 0-2 y cada R1 es un grupo tal como hidroxi, halogeno, trifluorometil hete4rociclilo y heterocicliloxi; R2 es halogeno, trifluorometilo o alquilo (1-6C), R3 es hidrogeno, halogeno o alquilo (1-6C); y R4 es cicloalquilo (3-6C), o sales farmaceuticamente aceptables del mismo; procesos para su preparacion, composiciones farmaceuticas que los contienen y su uso en el tratamiento de enfermedades o condiciones medicas mediadas por citocinas.
Bibliography:Application Number: MX2006PA04465