NOVEL CRYSTAL FORMS OF ONDANSETRON, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THE NOVEL FORMS AND METHODS FOR TREATING NAUSEA USING THEM

Ondansetron crystalline Forms A and B are useful in the treatment of nausea and vomiting. Form B has uniquely high melting point of about 244 degree C and both forms are stable against thermally induced polymorphic transition from 30 degree C up to their melting points. Las Formas A y B cristalinas...

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Bibliographic Details
Main Author TIVADAR TAMAS
Format Patent
LanguageEnglish
Spanish
Published 25.01.2005
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SEPARATION
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TRANSPORTING
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Summary:Ondansetron crystalline Forms A and B are useful in the treatment of nausea and vomiting. Form B has uniquely high melting point of about 244 degree C and both forms are stable against thermally induced polymorphic transition from 30 degree C up to their melting points. Las Formas A y B cristalinas de ondansetron son utiles en el tratamiento de nauseas y vomitos. La Forma B tiene un punto de fusion alto unico de 244 degree C y ambas formas son estables contra la transicion polimorfica inducida termicamente desde 30 degree C hasta su punto de fusion.
Bibliography:Application Number: MX2004PA10845