METHODS OF TREATING CANCER

Disclosed herein are methods of inhibiting tumor growth or producing tumor regression in a subject having a drug-resistant estrogen receptor alpha positive cancer or a mutant estrogen receptor alpha positive cancer. The methods entail administering to the subject a therapeutically effective amount o...

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Bibliographic Details
Main Authors HATTERSLEY Gary, GARNER Fiona
Format Patent
LanguageEnglish
Spanish
Published 19.03.2025
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Disclosed herein are methods of inhibiting tumor growth or producing tumor regression in a subject having a drug-resistant estrogen receptor alpha positive cancer or a mutant estrogen receptor alpha positive cancer. The methods entail administering to the subject a therapeutically effective amount of RAD 1901 having the structure (I) or a salt or solvate thereof. En este documento se describen métodos para inhibir el crecimiento tumoral o producir regresión tumoral en un sujeto que tiene un cáncer positivo a receptor de estrógeno alfa resistente a fármaco o un cáncer receptor positivo de receptor de estrógeno alfa. Los métodos implican administrar al sujeto una cantidad terapéuticamente eficaz de RAD1901 que tiene la estructura: (ver Fórmula) o una sal o solvato del mismo.
Bibliography:Application Number: MX20210005561