METHOD FOR INCREASING THE SENSITIVITY TO INSULIN BY 5-HT2 RECEPTOR ANTAGONISTS
The present invention refers to the participation of 5-HT2 serotonergic receptor with an increased insulin sensibility, mainly caused by the peripheral capture of glucose. The present invention is intended to use 5-HT2 receptor antagonist, such as indorrenate (hypertensive agent acting as central 5-...
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Main Authors | , |
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Format | Patent |
Language | English Spanish |
Published |
27.03.2019
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention refers to the participation of 5-HT2 serotonergic receptor with an increased insulin sensibility, mainly caused by the peripheral capture of glucose. The present invention is intended to use 5-HT2 receptor antagonist, such as indorrenate (hypertensive agent acting as central 5-HT1A receptor agonist) in pharmaceutical compositions for improving the insulin sensitivity, upon acting as 5-HT2 agonist in the periphery.
La presente invención se refiere a la participación de receptores serotonérgicos 5-TH2 con el incremento en la sensibilidad a la insulina, principalmente por aumentar la captura periférica de glucosa. La presente invención tiene como objetivo principal la utilización de agonistas de receptores serotonérgicos 5-HT2, como por ejemplo indorrenato (agente hipertensivo que actúa como agonista de receptores 5-HT1A centrales) en composiciones farmacéuticas para mejorar la sensibilidad a la insulina, al actuar como agonista 5-HT2 en la periferia. |
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Bibliography: | Application Number: MX20120011700 |