APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES

Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein. Se describen compuestos que inhiben la actividad de proteínas anti-apoptóticas Bcl-2, co...

Full description

Saved in:
Bibliographic Details
Main Authors Zhi-Fu TAO, Chang H. PARK, Gary T. WANG, Le WANG, Aaron R. KUNZER, Steven W. ELMORE, Xilu WANG, Andrew M. PETROS, Hong DING, Guillaume Laurent LESSENE, Michael D. WENDT, Lisa HASVOLD, Laura HEXAMER, William J. MCCLELLAN, Xiaohong SONG, Gerard M. SULLIVAN, George A. DOHERTY, Cheol-Min PARK, Milan BRUNCKO, Yujia DAI, Peter Malcom Colman, Andrew J. SOUERS, Robert A. MANTEI, Peter Edward Czabotar
Format Patent
LanguageEnglish
Spanish
Published 11.02.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein. Se describen compuestos que inhiben la actividad de proteínas anti-apoptóticas Bcl-2, composiciones que contienen los compuestos y métodos para tratar enfermedades durante las cuales se expresa la proteína anti-apoptótica Bcl-2.
Bibliography:Application Number: MX20140006161