DIHYDRO-BENZO-OXAZINE AND DIHYDRO-PYRIDO-OXAZINE DERIVATIVES

The invention relates to dihydro-benzo-oxazine and dihydro-pyrido-oxazine compounds of the formula (I) and/or pharmaceutically acceptable salts and/or solvates thereof, wherein Y, V, W, U, Q, R1, R5, R7 and R30 are as defined in the description. Such compounds are suitable for the treatment of a dis...

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Main Authors Giorgio CARAVATTI, Henrik MOEBITZ, Frédéric ZECRI, Alexander Baxter SMITH, Sylvie CHAMOIN, Karen KAMMERTOENS, Pascal FURET, Konstanze HURTH, Christoph KALIS, Nicolas SOLDERMANN, Romain WOLF, Ian LEWIS, Klemens HÖGENAUER
Format Patent
LanguageEnglish
Spanish
Published 08.01.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to dihydro-benzo-oxazine and dihydro-pyrido-oxazine compounds of the formula (I) and/or pharmaceutically acceptable salts and/or solvates thereof, wherein Y, V, W, U, Q, R1, R5, R7 and R30 are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of the PI3K enzymes. La invención se refiere a los compuestos de dihidro-benzooxazina y dihidro-pirido-oxazina de la fórmula (I) y/o a las sales farmacéuticamente aceptables y/o solvatos de los mismos: (ver Fórmula) en donde Y, V, W, U, Q, R1, R5, R7 y R30 son como se definen en la descripción. Estos compuestos son adecuados para el tratamiento de un trastorno o de una enfermedad que sea mediada por la actividad de las enzimas de PI3K.
Bibliography:Application Number: MX20140007687