NEW TH17 DIFFERENTIATION MARKERS FOR ACNE AND USES THEREOF

• Main Author: Isabelle CARLAVAN
• Format: Patent
• Language: English; Spanish
• Published: 07.07.2017
• Subjects: APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC,OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWERSUPPLY SYSTEMS; BASIC ELECTRIC ELEMENTS; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CONTROL OR REGULATION THEREOF; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUTPOWER; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER; CURRENT COLLECTORS; ELECTRICITY; ENZYMOLOGY; GENERATION; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; LINE CONNECTORS; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; TESTING; VINEGAR; WINE

The invention provides the use of ROR gamma t or ROR alpha, and their use to diagnose acne and/or to screen inhibitors of Th17 differentiation, notably in inhibiting ROR gamma t or ROR alpha and the use of these screened inhibitors in acne treatment. La presente invención se refiere a un uso del ADN o el ARNm que codifica ROR gamma t, o de la proteína ROR gamma t, como un marcador para el acné, cuyo acné es acné común, acné comedónico, acné papulopustular, acné papulocomedónico, acné nodulocístico, acné conglobado, acné queloideo de la nuca, acné recurrente militar, acné necrótico, acné neonatal, acné ocupacional, acné rosácea, acné senil, acné solar o acné relacionado con medicamentos.