POLYNUCLEOTIDES, COMPOSITIONS, AND METHODS FOR GENOME EDITING
Compositions and methods for gene editing are provided. In some embodiments, provided is a polynucleotide encoding an RNA-guided DNA binding agent such as N. meningitidis Cas9 that can provide one or more of improved editing efficiency, reduced immunogenicity, or other benefits. Se proporcionan comp...
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| Main Authors | , |
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| Format | Patent |
| Language | English Spanish |
| Published |
02.07.2024
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Compositions and methods for gene editing are provided. In some embodiments, provided is a polynucleotide encoding an RNA-guided DNA binding agent such as N. meningitidis Cas9 that can provide one or more of improved editing efficiency, reduced immunogenicity, or other benefits.
Se proporcionan composiciones y métodos para la edición génica. En algunas modalidades, se proporciona un polinucleótido que codifica un agente de unión al ADN guiado por ARN tal como Cas9 de N. meningitidis que puede proporcionar uno o más de eficacia de edición mejorada, inmunogenicidad reducida u otros beneficios. |
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| AbstractList | Compositions and methods for gene editing are provided. In some embodiments, provided is a polynucleotide encoding an RNA-guided DNA binding agent such as N. meningitidis Cas9 that can provide one or more of improved editing efficiency, reduced immunogenicity, or other benefits.
Se proporcionan composiciones y métodos para la edición génica. En algunas modalidades, se proporciona un polinucleótido que codifica un agente de unión al ADN guiado por ARN tal como Cas9 de N. meningitidis que puede proporcionar uno o más de eficacia de edición mejorada, inmunogenicidad reducida u otros beneficios. |
| Author | STRETZ Lindsey Jean MULEPATI Sabin |
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| DocumentTitleAlternate | POLINUCLEOTIDOS, COMPOSICIONES Y METODOS PARA LA EDICION DEL GENOMA. |
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| Snippet | Compositions and methods for gene editing are provided. In some embodiments, provided is a polynucleotide encoding an RNA-guided DNA binding agent such as N.... |
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| SubjectTerms | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| Title | POLYNUCLEOTIDES, COMPOSITIONS, AND METHODS FOR GENOME EDITING |
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