POLYNUCLEOTIDES, COMPOSITIONS, AND METHODS FOR GENOME EDITING

Compositions and methods for gene editing are provided. In some embodiments, provided is a polynucleotide encoding an RNA-guided DNA binding agent such as N. meningitidis Cas9 that can provide one or more of improved editing efficiency, reduced immunogenicity, or other benefits. Se proporcionan comp...

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Bibliographic Details
Main Authors STRETZ Lindsey Jean, MULEPATI Sabin
Format Patent
LanguageEnglish
Spanish
Published 02.07.2024
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Compositions and methods for gene editing are provided. In some embodiments, provided is a polynucleotide encoding an RNA-guided DNA binding agent such as N. meningitidis Cas9 that can provide one or more of improved editing efficiency, reduced immunogenicity, or other benefits. Se proporcionan composiciones y métodos para la edición génica. En algunas modalidades, se proporciona un polinucleótido que codifica un agente de unión al ADN guiado por ARN tal como Cas9 de N. meningitidis que puede proporcionar uno o más de eficacia de edición mejorada, inmunogenicidad reducida u otros beneficios.
Bibliography:Application Number: MX20240005242