IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS

The present application discloses compounds having the following formula (I): or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, and R4 are defined in the specification, as well as methods of making and using the compounds disclosed herein for treating or ameliorating an IL-17 mediate...

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Main Authors SHIREMAN Brock T, VENABLE Jennifer D, MCCARVER Stefan, MEDUNA Steven P, VALDES Alexander E, GOLDBERG Steven D, BEHENNA Douglas C, XUE Xiaohua, GORDON Deane, WU Dongpei, LOSKOT Steven A, HANNA Luke E
Format Patent
LanguageEnglish
Spanish
Published 19.06.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present application discloses compounds having the following formula (I): or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, and R4 are defined in the specification, as well as methods of making and using the compounds disclosed herein for treating or ameliorating an IL-17 mediated syndrome, disorder and/or disease. La presente solicitud describe compuestos que tienen la siguiente fórmula: (VER FORMULA) o sales farmacéuticamente aceptables de estos, en donde R1 , R2 , R3 , y R4 se definen en la especificación, así como métodos para elaborar y usar los compuestos descritos en la presente descripción para tratar o mejorar un síndrome, trastorno y/o enfermedad mediada por la IL-17.
Bibliography:Application Number: MX20240003770